What electrolyte abnormality is commonly associated with sarcoidosis?

What electrolyte abnormality is commonly associated with sarcoidosis?

• A. Bicarbonate
• B. Calcium
• C. Potassium
• D. Sodium

Answer: (B)

In the context of sarcoidosis, hypercalcemia is a common and significant electrolyte abnormality. This condition often occurs due to the increased production of calcitriol (active vitamin D) by activated macrophages within the granulomas typical of sarcoidosis. As a result, patients with sarcoidosis may experience elevated serum calcium levels, which can lead to various symptoms, including fatigue, weakness, and, in severe cases, kidney dysfunction due to hypercalcemia-related complications. The mechanism linking sarcoidosis to hypercalcemia illustrates how systemic inflammatory processes can impact calcium homeostasis, making it a critical aspect of the disease's clinical management. Monitoring calcium levels in patients diagnosed with sarcoidosis is essential to prevent potential complications associated with elevated calcium levels.

In the context of sarcoidosis, hypercalcemia is a common and significant electrolyte abnormality. This condition often occurs due to the increased production of calcitriol (active vitamin D) by activated macrophages within the granulomas typical of sarcoidosis. As a result, patients with sarcoidosis may experience elevated serum calcium levels, which can lead to various symptoms, including fatigue, weakness, and, in severe cases, kidney dysfunction due to hypercalcemia-related complications.

The mechanism linking sarcoidosis to hypercalcemia illustrates how systemic inflammatory processes can impact calcium homeostasis, making it a critical aspect of the disease's clinical management. Monitoring calcium levels in patients diagnosed with sarcoidosis is essential to prevent potential complications associated with elevated calcium levels.